Antimicrobial activities of herbal plants from Uzbekistan against human pathogenic microbes
- PDF / 966,677 Bytes
- 8 Pages / 595.276 x 790.866 pts Page_size
- 77 Downloads / 186 Views
MINI REVIEW
Antimicrobial activities of herbal plants from Uzbekistan against human pathogenic microbes Dilfuza Egamberdieva1,2 · Dilfuza Jabborova3 · Svetlana Babich4 · Sokhiba Xalmirzaeva4 · Kamaliddin Salakhiddinov4 · Madamin Madazimov4 Received: 1 August 2020 / Revised: 29 October 2020 / Accepted: 3 November 2020 © The Author(s) 2020
Abstract In traditional medicine of Uzbekistan, around 20% of herbal plants are used to treat various ailments, including diseases caused by pathogenic bacteria and fungi. Though conventional medicinal plants are common in Uzbekistan, many plant species potentially useful for new pharmaceuticals are less studied. They contain various biological compounds with antibacterial and antifungal activities, that could be developed into drugs. The search for novel antimicrobial compounds, especially against multidrug-resistant pathogens from aromatic and herbal plants is an essential scientific research line. However, the antimicrobial properties of several medicinally important plants from various countries are still unknown. This review aims to provide an up-to-date report on the antimicrobial activity of medicinal plants endemic to Uzbekistan widely used in traditional medicine. Keywords Medicinal plants · Metabolites · Antibacterial activity · Antifungal activity Uzbekistan
Introduction It is estimated that about 50,000 plant species were screened for medicinal properties and used by 80% of the world’s population to treat numerous human diseases (SaslisLagoudakis et al. 2014; Chen et al. 2016). Uzbekistan is known for its endemism, in which 9% of 4500 species of vascular plants are considered endemic (Mamedov et al. 2004). Though traditional medicinal plants are common in Uzbekistan, many plant species potentially useful for new pharmaceuticals are less studied. The remedies derived from natural resources are widely used to treat numerous illnesses, including respiratory and urinary problems, gastrointestinal, and skin disorders as age-old tradition (McChesney et al. * Dilfuza Egamberdieva [email protected] 1
Faculty of Biology, National University of Uzbekistan, Tashkent, Uzbekistan
2
Leibniz Centre for Agricultural Landscape Research (ZALF), Müncheberg, Germany
3
Institute of Genetics and Plant Experimental Biology, Academy of Sciences of Uzbekistan, Tashkent, Uzbekistan
4
Andijan State Medical Institute, Otabekov Str. 1., Andijan, Uzbekistan
2007). Since the cost of synthetic, medicinal drugs is high, the developing countries are still using herbal plants or their derivates to treat common diseases (Abu-Irmaileh and Afifi 2000). It is known that multidrug-resistant bacterial pathogens signify a growing public health threat. Therefore, there is a continuous need for effective natural therapeutic agents (Compean and Ynalvez 2014). The investigation of aromatic and herbal plants for their biologically active constituents might lead to discovery of new drugs with antimicrobial activities (Cushnie and Lamb 2005; Shrivastava et al. 2015). The medicinal plants co
Data Loading...
