Association between SLC44A4 - NOTCH4 SNPs and serum lipid levels in the Chinese Han and Maonan ethnic groups
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RESEARCH
Association between SLC44A4‑NOTCH4 SNPs and serum lipid levels in the Chinese Han and Maonan ethnic groups Peng‑Fei Zheng1, Rui‑Xing Yin1,2,3* , Yao‑Zong Guan1, Bi‑Liu Wei1, Chun‑Xiao Liu1 and Guo‑Xiong Deng1
Abstract Background: The current research was to assess the relationship of the solute carrier family 44 member 4 (SLC44A4) rs577272, notch receptor 4 (NOTCH4) rs3134931 SNPs and serum lipid levels in the Han and Maonan ethnic groups. Methods: The genetic makeup of the SLC44A4 rs577272 and NOTCH4 rs3134931 SNPs in 2467 unrelated subjects (Han, 1254; Maonan,1213) was obtained by using polymerase chain reaction and restriction fragment length poly‑ morphism technique, combined with gel electrophoresis, and confirmed by direct sequencing. Results: The genotype frequencies of SLC44A4 rs577272 and NOTCH4 rs3134931 SNPs were different between Han and Maonan populations (P
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