Bartter Syndrome Masquerading as Acute Kidney Injury in a Neonate
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3. Rodríguez-Núñez A, López-Herce J, Gil-Antón J, Hernández A, Rey C, RETSPED Working Group of the Spanish Society of Pediatric Intensive Care. Rescue treatment with terlipressin in children with refractory septic shock: A clinical study. Crit Care. 2006;10:R20. 4. Radicioni M, Troiani S, Camerini PG. Effects of terlipressin on pulmonary artery pressure in a septic cooled infant: an echocardiographic assessment. J Perinatol. 2012;32:89-5. 5. Evora PR, Pearson PJ, Schaff HV. Arginine vasopressin induces endothelium-dependent vasodilatation of the pulmonary artery. V1-receptor-mediated production of nitric oxide.Chest. 1993;103:1241-5. 6. Stathopoulos L, Nicaise C, Michel F, Thomachot L, Merrot T, Lagier P, et al. Terlipressin as rescue therapy for refractory pulmonary hypertension in a neonate with a congenital diaphragmatic hernia. J Pediatr Surg. 2011;46:e19-21.
2IBIOMED (Biomedicine Institute of Leon, University of Leon,
Leon;3 Neonatal Intensive Care Unit,Complejo Asistencial Universitario de Leon; and 4Pediatric Intensive, Intermediate and Palliative Care Section,ComplejoHospitalarioUniversitario de Santiago, Santiago de Compostela; Spain. *[email protected]
REFERENCES 1. Fuloria M, Aschner JL. Persistent pulmonary hypertension of the newborn.Semin Fetal Neonatal Med. 2017;22:220-6. 2. Masarwa R, Paret G, Perlman A, Reif S, Raccah BH, Matok I. Role of vasopressin and terlipressin in refractory shock compared to conventional therapy in the neonatal and pediatric population: A systematic review, metaanalysis, and trial sequential analysis. Crit Care. 2017;21:1.
Bartter Syndrome Masquerading as Acute Kidney Injury in a Neonate
improved and he was weaned from ventilator after 4 days. The renal parameters normalized after 20 cycles of dialysis.Blood and urine cultures were negative.Post-dialysis the child developed polyuria with a daily urine output >8 mL/kg/day. The infant continued to have polyuria inspite of measures to decrease urine output. The infant developed metabolic alkalosis despite acute kidney injury and polyuria. The blood pressures were in normal range. The urine examination showed, red blood cells, granular casts and proteinuria. Urinary electrolytes values showed urine osmolality – 133.2 mOsm/kg (normal 500 – 850 mOsm/kg), urinary chloride–66 mEq/L (normal
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