Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma
This astute volume brings together the latest expert research on adamantinomatous craniopharyngiomas (ACPs). ACPs are histologically benign but clinically aggressive tumors exhibiting a high propensity for local invasion into the hypothalamus, optic and v
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Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma
Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma
Juan Pedro Martinez-Barbera Cynthia Lilian Andoniadou Editors
Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma
Editors Juan Pedro Martinez-Barbera Developmental Biology and Cancer Programme Birth Defects Research Centre Institute of Child Health University College London London, UK
Cynthia Lilian Andoniadou Craniofacial Development and Stem Cell Biology King’s College London London, UK
ISBN 978-3-319-51888-6 ISBN 978-3-319-51890-9 (eBook) DOI 10.1007/978-3-319-51890-9 Library of Congress Control Number: 2017933569 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
This edited book, Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma, aims to present an up-to-date picture of the current efforts for the effective treatment and management of the paediatric tumour adamantinomatous craniopharyngioma (ACP) and how patient management can be tailored in the future. The book was triggered by a lack of comprehensive publications bringing together a global view of all relevant aspects of these tumours. Here we bring a multidisciplinary group of international experts that present the current views on ACP diagnosis and management, as well as recent research generating mouse models for these tumours and yielding findings that have the potential to impact on future patient treatments. The first two chapters of this book focus on the pathogenesis of human ACP and the molecular analyses that have been carr
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