Basic and Clinical Aspects of Helicobacter pylori Infection
A century ago the Italian pathologist Bizzozero described the relationships between spiral bacteria and the mammalian gastro intestinal tract. Since 1982, when Helicobacter pylori was discovered, gastroduodenal disease have been completely revised as a c
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Basic and Clinical
Aspects of Helicobacter pylori
Infection
With 76 Figures
Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona Budapest
Professor G. Gasbarrini I. Patologia Medica
Polic1inico S. Orsola Via Massarenti 9 1-40138 Bologna Italy Dr. S. Pretolani I. Patologia Medica
Polic1inico S. Orsola Via Massarenti 9 1-40138 Bologna Italy
ISBN-13: 978-3-642-78233-6 e-ISBN-13: 978-3-642-78231-2 DOl: 10.1007/978-3-642-78231-2 Library of Congress Cataloging·in-Publication Data. Basic and Clinical Aspects of Helicobacter pylori infection / G. Gasbarrini, S. Pretolani (eds.). p. cm. Proceedings of the Fourth Workshop of the European Helicobacter Pylori Study Group, held in Bologna, Italy, Nov. 1991. Includes bibliographical references and index. ISBN-13: 978-3-642-78233-6 I. Helicobacter pylori infections - Congresses. I. Gasbarrini, G. II. Pretolani, S. (Stefano), 1956- . III. European Helicobacter Pylori Study Group, Workshop (4th; 1991; Bologna, Italy) [DNLM: I. Helicobacter Infections - pathology - congresses. 2. Helicobacter Infections - drug therapy - congresses. 3. Helicobacter pylori - pathogenicity congresses. 4. Peptic Ulcer-parasitology - congresses. 5. Gastritis - parasitology - congresses. WC 200 8311 1991] - QR201.H44B37 1993 616.9'31 - dc20 DNLM/DLC 93-43056
© Springer-Verlag Berlin Heidelberg 1994 Softcover reprint of the hardcover 1st edition 1994 The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Typesetting: Thomson Press (India) Ltd., New Delhi 23/3130/SPS - 543210 - Printed on acid-free paper
Preface
A century ago the Italian pathologist Bizzozero described the relationships between spiral bacteria and the mammalian gastrointestinal tract. Since 1982, when Helicobacter pylori was discovered, gastroduodenal disease have been completely revised as a consequence of the results of basic and clinical research in this field. Progress in understanding the pathogenesis of this bacterium has been made by studying H. pylori infection in animal models. More specific diagnostic tools have been developed using new molecular biology techniques. Future trends are directed towards preparing a specific H. pylori vaccine. A new classification for gastritis, the Sydney System, including H. pylori gastritis, was proposed in 1990. As concerns the clinical approach to peptic ulcer disease in the 1990's, the majority of authors agree on the importance of H. pylori eradication. Moreover, recent clinical studies suggest that H. pylori infection can be associated with other gastroduodenal diseases, such as non ulcer dyspepsia and gastric c
