Basics of Flow Microreactor Synthesis
This book provides in a concise form the principles and applications of flow microreactors in organic and polymer synthesis. Recently, it became possible to conduct chemical reactions in a flow reactor in laboratory synthesis. The flow microreactor enable
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Jun-ichi Yoshida
Basics of Flow Microreactor Synthesis
123
SpringerBriefs in Molecular Science
More information about this series at http://www.springer.com/series/8898
Jun-ichi Yoshida
Basics of Flow Microreactor Synthesis
123
Jun-ichi Yoshida Kyoto University Kyoto Japan
ISSN 2191-5407 ISSN 2191-5415 (electronic) SpringerBriefs in Molecular Science ISBN 978-4-431-55512-4 ISBN 978-4-431-55513-1 (eBook) DOI 10.1007/978-4-431-55513-1 Library of Congress Control Number: 2015936380 Springer Tokyo Heidelberg New York Dordrecht London © The Author(s) 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer Japan KK is part of Springer Science+Business Media (www.springer.com)
Preface
This published work is intended to serve as a sourcebook on flow microreactor synthesis for students and researchers who are not familiar with this field. This book is aimed at developing a deeper understanding of chemical reactions by taking advantage of the characteristic features of flow microreactors. This book is not a compilation of all fields of flow microreactor synthesis, but it focuses on highresolution reaction time control and fast micromixing. I do hope that the topics discussed in this book will be sufficient to interest a wide range of readers in this fascinating field of chemistry and to encourage them to try chemical synthesis using flow microreactors. On each topic, I usually focus on the works that have been done in my research group as examples simply because I know them more in detail than other works reported in the literature. I hope that these examples and the accompanying discussions will serve as a guide to how to use a flow microreactor for chemical synthesis. I thank the members of my research group, including Dr. Aiichiro Nagaki, who have performed extensive work to develop the chemistry described in this book. I also appreciate the financial support of a Grant-in-Aid for Scientific Research and NEDO projects to enable our research i
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