Beta-Lactams Novel Synthetic Pathways and Applications
This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, th
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Beta-Lactams Novel Synthetic Pathways and Applications
Beta-Lactams
Bimal K. Banik Editor
Beta-Lactams Novel Synthetic Pathways and Applications
123
Editor Bimal K. Banik Community Health System of South Texas Edinburg, TX USA
ISBN 978-3-319-55620-8 DOI 10.1007/978-3-319-55621-5
ISBN 978-3-319-55621-5
(eBook)
Library of Congress Control Number: 2017934874 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Synthesis and biological investigations of b-lactams have been very intensely studied for more than 7 decades because of their powerful clinical activity, as well as their potential use as intermediates for the synthesis of diverse heterocyclic compounds with controlled stereochemistry. Significant research has been performed by scientists in this area, and it is a good time to summarize useful research on b-lactams. As a result of these studies, many authors have published their research in various journals and books. A number of studies have resulted in patents. Earlier, the editor of this book has edited two books on beta b-lactams that were written by eminent authors in this field and published by Springer. In the current book, the editor also has selected leaders in this field to write book chapters on various aspects of b-lactam science. Bhalla and his group have described synthesis of diverse b-lactams and identified the role of appended hetero groups on the activity in Chapter “Synthesis of Diverse bLactams: Role of Appended Hetero Moiety on Its Activity”. Bari et al. have demonstrated the use of transition metal reagents in the synthesis of b-lactams through selective approaches i
