Bevacizumab
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Bevacizumab Rectovaginal fistula in an elderly patient: case report A 72-year-old woman with a history of rectal cancer presented with new-onset foul-smelling vaginal discharge; that same month, she had finished a 6-month course of bevacizumab [Avastin; dosage not stated; time to reaction onset not clearly stated]. A large rectovaginal fistula at the site of a previous anastomosis was observed on CT scan; no sign of local recurrence was found. [Patient outcome not stated.] Author comment: "This delayed onset of a rectovaginal fistula in proximity to Bevacizumab infusion suggests that the drug my cause fistulas in previously operated sites." Ley EJ, et al. Delayed rectovaginal fistula: a potential complication of bevacizumab (Avastin). Diseases of the Colon and Rectum 50 (Suppl. 1): 930, No. 801090204 6, Jun 2007 - USA
0114-9954/10/1162-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Reactions 28 Jul 2007 No. 1162
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