Biochemistry and Cell Biology of Ageing: Part I Biomedical Science

This volume of the Subcellular Biochemistry series, Biochemistry and Cell Biology of Ageing: Part I is devoted broadly to Biomedical aspects of Ageing. The 17 chapters included in the book, contributed by knowledgeable authors, review many impor

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J. Robin Harris Viktor I. Korolchuk Editors

Biochemistry and Cell Biology of Ageing: Part I Biomedical Science

Subcellular Biochemistry Volume 90

Series editor J. Robin Harris Institute of Molecular Physiology, Johannes Gutenberg University, Mainz, Germany

The book series SUBCELLULAR BIOCHEMISTRY is a renowned and well recognized forum for disseminating advances of emerging topics in Cell Biology and related subjects. All volumes are edited by established scientists and the individual chapters are written by experts on the relevant topic. The individual chapters of each volume are fully citable and indexed in Medline/Pubmed to ensure maximum visibility of the work. Series Editor J. Robin Harris, Institute of Molecular Physiology, Johannes Gutenberg University, Mainz, Germany International Advisory Editorial Board T. Balla, National Institutes of Health, NICHD, Bethesda, USA Tapas K. Kundu, JNCASR, Bangalore, India A. Holzenburg, The University of Texas Rio Grande Valley, Harlingen, USA S. Rottem, The Hebrew University, Jerusalem, Israel X. Wang, Jiangnan University, Wuxi, China More information about this series at http://www.springer.com/series/6515

J. Robin Harris  •  Viktor I. Korolchuk Editors

Biochemistry and Cell Biology of Ageing: Part I Biomedical Science

Editors J. Robin Harris Institute of Molecular Physiology Johannes Gutenberg University Mainz, Germany

Viktor I. Korolchuk Newcastle University Newcastle upon Tyne, UK

ISSN 0306-0225 Subcellular Biochemistry ISBN 978-981-13-2834-3    ISBN 978-981-13-2835-0 (eBook) https://doi.org/10.1007/978-981-13-2835-0 Library of Congress Control Number: 2018965214 © Springer Nature Singapore Pte Ltd. 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21