Developmental Biology and Ageing
First and foremost, a systems biology approach to developmental biology involves the extension of signalling to the intercellular domain. An ideal and highly tractable model organism for studying this process is Arabidopsis. Plant development in important
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Frederick B. Marcus
Bioinformatics and Systems Biology Collaborative Research and Resources
Dr. Frederick B. Marcus Principal Scientific Officer Research Directorate General European Commission 1049 Brussels Belgium [email protected]
DISCLAIMER: The contents of this book are based upon referenced, publicly available sources, specifically books, publications and websites. Although at the time of publication, the author is an employee of the European Commission, this book is his work alone and it is not sponsored by the Commission, nor is it a Commission publication. The author is not receiving any royalties on this book. The contents may not in any circumstances be regarded as stating an official position of the Commission. Neither the Commission nor the author nor any person acting on behalf of the Commission is responsible for the use that might be made of the contents of this book. Material in this book is only an indicative guide to accessing the officially approved material available in Commission websites and publications.
ISBN 978-3-540-78352-7 e-ISBN 978-3-540-78353-4 DOI: 10.1007/978-3-540-78353-4 Library of Congress Control Number: 2008921486 © 2008 Springer-Verlag Berlin Heidelberg This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Cover design: WMX Design GmbH, Heidelberg, Germany Printed on acid-free paper 9 8 7 6 5 4 3 2 1 0 springer.com
I dedicate this book to my parents Marvin and Aileen Marcus, my Wife Rosemary and my Brother Jeff and my departed grandparents Jennie Marcus and Reuben and Anne Axler, who gave me the greatest gift, love, and all that goes with it.
Preface
Purpose of This Book: This textbook on collaborative research in bioinformatics and systems biology, which are key elements of modern biology and health research, highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research across Europe and the world, resulting in world-class contributions to bioinformatics and systems biology. Central Themes: A number of themes a
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