Biosensors for toxic metals, polychlorinated biphenyls, biological oxygen demand, endocrine disruptors, hormones, dioxin
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REVIEW
Biosensors for toxic metals, polychlorinated biphenyls, biological oxygen demand, endocrine disruptors, hormones, dioxin, phenolic and organophosphorus compounds: a review Madan L. Verma1 · Varsha Rani2 Received: 11 September 2020 / Accepted: 8 October 2020 © Springer Nature Switzerland AG 2020
Abstract The growing pollution by hazardous agents is a major concern due to pollutant transfer to water, air, soil and food. Since actual analytical methods are limited, there is a need for detectors that are more sensitive, more selective, faster and cheaper. For instance, advanced portable biosensors have better sensitivity compared to classical diagnostic devices. Here, we review ultrasensitive detection of pollutants by biosensors. In particular, nanobiosensors display remarkable nanomolar to picomolar detection of various pollutants including heavy metals, pesticides, endocrine disruptors, dioxin, biological oxygen demand and microbial pathogens. Keywords Biosensor · Nanobiosensor · Pollutant · Environment · Detection · Selectivity · Sensitivity
Introduction Biosensor technology is one of the emerging technologies that have produced a major impact in the diverse sectors ranging from healthcare, food, pharmaceutical, agriculture and environmental industries (Campana et al. 2019; Verma 2017a; Verma et al. 2010). According to a new market report published in 2020 by Allied Market Research “Biosensors market by product (wearable biosensors and non-wearable biosensors), technology (electrochemical biosensors, optical biosensors, piezoelectric biosensors, thermal biosensors and nanomechanical biosensors): Global opportunity analysis and industry forecast”, the global biosensors market size was valued at $17,500 million in 2018 and is expected to reach $38,600 million by 2026, registering a compound annual growth rate of 10.4% from 2019 to 2026 (https://www.allie dmarketresearch.com/biosensors-market).
* Madan L. Verma [email protected]; [email protected] 1
Department of Biotechnology, School of Basic Sciences, Indian Institute of Information Technology, Una, Himachal Pradesh 177220, India
Department of Biotechnology, Shoolini University, Solan, Himachal Pradesh 173229, India
2
Biosensors are remarkable portable tools employed for the detection of chemical and biological components of clinical, food and environmental monitoring (Kalyani et al. 2020). Biosensors are endowed with unique properties like higher specificity, rapid response, compacted size, higher selectivity, higher stability, lower cost and user-friendly nature that make them the ideal sensing device. It combines a biologically derived recognition entity with a transducer for developing biochemical parameters quantitatively (Mishra et al. 2018; Verma 2017b). Biological elements can be an antibody, enzyme, cell receptors, nucleic acids and microbes, while the sensing element can be an electric potential and electric current (Jain et al. 2010). Different variants of the biosensors are based on the working mechanism of the tra
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