Brain-Derived Neurotrophic Factor (BDNF)

This volume discusses the latest techniques and methodologies used in the neurotrophin field to study the physiology of the Brain-Derived Neurotrophic Factor (BDNF). The book provides the tools essential to any researcher that intends to explore the pecul

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Carlos B. Duarte Enrico Tongiorgi Editors

Brain-Derived Neurotrophic Factor (BDNF)

NEUROMETHODS

Series Editor Wolfgang Walz University of Saskatchewan Saskatoon, Canada

For further volumes: http://www.springer.com/series/7657

Brain-Derived Neurotrophic Factor (BDNF) Edited by

Carlos B. Duarte Center for Neuroscience and Cell Biology and Department of Life Sciences, University of Coimbra, Coimbra, Portugal

Enrico Tongiorgi BRAIN Center for Neuroscience, Department of Life Sciences, University of Trieste, Trieste, Italy

Editors Carlos B. Duarte Center for Neuroscience and Cell Biology and Department of Life Sciences University of Coimbra Coimbra, Portugal

Enrico Tongiorgi BRAIN Center for Neuroscience Department of Life Sciences University of Trieste Trieste, Italy

ISSN 0893-2336 ISSN 1940-6045 (electronic) Neuromethods ISBN 978-1-4939-8969-0 ISBN 978-1-4939-8970-6 (eBook) https://doi.org/10.1007/978-1-4939-8970-6 Library of Congress Control Number: 2019934806 © Springer Science+Business Media, LLC, part of Springer Nature 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Humana Press imprint is published by the registered company Springer Science+Business Media, LLC, part of Springer Nature. The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.

Series Preface Experimental life sciences have two basic foundations: concepts and tools. The Neuromethods series focuses on the tools and techniques unique to the investigation of the nervous system and excitable cells. It will not, however, shortchange the concept side of things as care has been taken to integrate these tools within the context of the concepts and questions under investigation. In this way, the series is unique in that it not only collects protocols but also includes theoretical background information and critiques which led to the methods and their de