Cadaveric tissue retrieval service for research: one-year review and options for the future
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Cell and Tissue Banking (2006) 7:211–214 DOI 10.1007/s10561-005-5659-2
Cadaveric tissue retrieval service for research: one-year review and options for the future* Christopher Womack*, Jane Pope, Alison Jack and Cathy Semple Tissue Acquisition Unit, Peterborough District Hospital, Thorpe Road, Peterborough PE3 6DA, UK; *Author for correspondence (e-mail: [email protected]; phone: +44-1733-874648; fax: +44-1733 -874971) Received 30 November 2004; accepted in revised form 30 November 2005
Key words: Commercial biomedical research, Human cadaver tissue
Abstract The Tissue Acquisition Unit at Peterborough has an established service for collecting cadaveric human tissue for research. A one-year, on-going, in-house review was undertaken to evaluate the cost- and timeeffectiveness of the service. The review identified referrals that failed to result in post mortem tissue retrieval. Only 28.6% of potential donors referred to the Unit led to successful tissue retrieval and the main reason for failure was post mortem time delay in some cases related to distance of location of the body from the Unit. The evolving novel role of the Pathology Liaison Nurses in the Unit is expected to increase the proportion of tissue acquisition from the local population and provide a more efficient service for donors and their families and researchers who use human tissue.
Introduction The Tissue Acquisition Unit at Peterborough Hospitals NHS Trust has an established system for on-site post mortem tissue retrieval for research (Womack et al. 2001, 2002). All retrievals are performed after consent has been obtained from donors and/or donor families as appropriate. Most of the tissue is used for research by commercial companies. The majority of donors are referred from coordinators of the National Blood Service, Tissue Services (NBSTS) in the National Health Service. In addition, the Unit keeps its own donor register and referrals are also made from other sources. A referral involves different staff groups within and outside the hospital (Figure 1) * This work was presented at the BATB Annual Scientific meeting in Edinburgh, April 2004.
and as a result, the procedure leading to each donation is complex and time consuming. Departmental reorganisation resulted in responsibility for responding to referrals passing from an administrator and biomedical scientist, to the Pathology Liaison Nurses (PLN) in the Unit in January 2003. The unpredictability and time constraints of the supporting on-call arrangements provided 09.00–22.00 h 7 days per week had the potential to adversely affect the other work of the PLNs (Womack et al. 2003). We undertook an ongoing evaluation of the cost- and timeeffectiveness of our on-call donor referral system throughout the year 2003. At the same time, we identified and investigated reasons why referrals did not progress to retrievals. This information was used to identify future options for the cadaveric retrieval service in a changing local and national environment where hospital and community
212 health services ar
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