Can the systemic immune inflammation index preoperatively predict nasal polyp subtypes?

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RHINOLOGY

Can the systemic immune inflammation index preoperatively predict nasal polyp subtypes? Mehmet Emre Sivrice1   · Erdoğan Okur1   · Hasan Yasan1   · Mustafa Tüz1   · Yusuf Çağdaş Kumbul1   · Vural Akın1  Received: 22 May 2020 / Accepted: 24 June 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Purpose  Chronic rhinosinusitis with nasal polyps can be classified as eosinophilic or neutrophilic based on the major inflammatory cell type in the tissue. There is a need for predictive parameters to enable rhinologists to identify the type of nasal polyp in a patient without surgery. The aim of the present study was to test the predictive value of the markers of inflammation to estimate eosinophilic nasal polyps. Methods  The study analyzed 299 patients who underwent sinus surgery for nasal polyps from 2012 to 2019. Patients were divided into two groups according to pathology results (eosinophilic polyps = group 1, neutrophilic polyps = group 2). The values of preoperative complete blood count, systemic immune inflammation index, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio were compared. Results  In our series, results of ROC analyses for both mean eosinophil count and systemic immune inflammation index were statistically significant. For the eosinophil count (AUC = 0.681, p