Cardiovascular Regenerative Medicine Tissue Engineering and Clinical
This book is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of cardiovascular disease. It provides a much-needed review of the rapid development and evolution of bio-fabrication techniques to engineer cardiov
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Cardiovascular Regenerative Medicine
Vahid Serpooshan • Sean M. Wu Editors
Cardiovascular Regenerative Medicine Tissue Engineering and Clinical Applications
Editors Vahid Serpooshan Department of Biomedical Engineering Emory University School of Medicine and Georgia Institute of Technology Atlanta, GA USA
Sean M. Wu Cardiovascular Institute and Department of Medicine, Division of Cardiovascular Medicine, Stanford University Stanford, CA USA
Department of Pediatrics Emory University School of Medicine Atlanta, GA USA Children’s Healthcare of Atlanta Atlanta, GA USA
ISBN 978-3-030-20046-6 ISBN 978-3-030-20047-3 (eBook) https://doi.org/10.1007/978-3-030-20047-3 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Cardiovascular Regenerative Medicine: An Introduction
In the past decades, the progress made in cardiovascular regenerative medicine has been nothing but spectacular. From an improved understanding of how the heart develops in the earliest stages of fetal development to barriers that prevents an adult cardiomyocytes to undergo cell division, we have come a long way to identify potential therapeutic strategies that can mediate the repair and regeneration of the mammalian heart. While much scientific progress has been celebrated and showcased at research conferences and in published studies, the stark reality remains that cardiovascular disease is the number one cause of death in the Western world with rapidly rising incidence in developing countries such as China and India. Given this, the interest in developing new therapies for treating, if not curing, damaged hearts remains strong. Therapeutic approaches to treat cardiovascular disea
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