Changes of hematological and immunological parameters in COVID-19 patients
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ORIGINAL ARTICLE
Changes of hematological and immunological parameters in COVID‑19 patients Xiaohong Yuan1 · Wanling Huang1 · Bing Ye2 · Cunrong Chen2 · Rongfeng Huang3 · Feng Wu4 · Qin Wei5 · Wei Zhang5 · Jianda Hu1 Received: 17 May 2020 / Revised: 11 June 2020 / Accepted: 23 June 2020 © Japanese Society of Hematology 2020
Abstract The aim of this study was to identify the changes of hematologic and immunological parameters in COVID-19 patients. We collected and analyzed the data of 117 patients who were laboratory confirmed as SARS-CoV-2 infection. The cases were divided into regular group, severe group and critically ill group according to the sixth edition scheme for COVID-19 diagnosis and treatment of China. The laboratory tests included blood routine, cellular and humoral immunity indices, biochemical detections and inflammatory biomarker. Compared with regular patients, severe and critically ill patients had significantly lower lymphocyte count (p
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