Cholesterol Its Functions and Metabolism in Biology and Medicine

Experts investigate the biochemical and biomedical aspects of cholesterol, addressing its metabolism in normal and disease states. They discuss a broad range of topics, including key steps in the cholesterol biosynthetic pathway, and the role of cholester

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28

Cholesterol: Its Functions and Metabolism in Biology and Medicine

SUBCELLULAR BIOCHEMISTRY SERIES EDITOR J. ROBIN HARRIS, Institute of Zoology, University of Mainz, Mainz, Gennany

ASSISTANT EDITORS H. J. HILDERSON, University of Antwerp, Antwerp, Belgium B. B. BISWAS, University of Calcutta, Calcutta, India

Recent Volumes in This Series: Volume 19

Endocytic Components: Identification and Characterization Edited by J. J. M. Bergeron and J. R. Harris

Volume 20

Mycoplasma Cell Membranes Edited by S. Rottem and I. Kahane

Volume 21

Endoplasmic Reticulum Edited by N. Borgese and J. R. Harris

Volume 22

Membrane Biogenesis Edited by A. H. Maddy and J. R. Harris

Volume 23 Volume 24

Physicochemical Methods in the Study of Biomembranes Edited by Herwig J. Hilderson and Gregory B. Ralston Proteins: Structure, Function, and Engineering Edited by B. B. Biswas and Siddhartha Roy

Volume 25

Ascorbic Acid: Biochemistry and Biomedical Cell Biology Edited by J. Robin Harris

Volume 26

myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction Edited by B. B. Biswas and Susweta Biswas

Volume 27

Biology of the Lysosome Edited by John B. Lloyd and Robert W. Mason

Volume 28

Cholesterol: Its Functions and Metabolism in Biology and Medicine Edited by Robert Bittman

A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.

Subcellular Biochemistry Volume 28 Cholesterol: Its Functions and Metabolism in Biology and Medicine Edited by

Robert Bittman Queens College ofThe City University of New York Flushing, New York

SPRINGER SCIENCE+BUSINESS MEDIA, LLC

The Library of Congress cataloged the first volume of this title as follows: Sub-cellular biochemistry. London, New York, Plenum Press. v. illus. 23 cm. quarterly. Began with Sept. 1971 issue. Cf. New serial titles. 1. Cytochemistry-Periodicals. 2. CeH organelles-Periodicals. QH61l.S84 574.8'76

73-643479

ISSN 0306-0225

ISBN 978-1-4613-7707-8

ISBN 978-1-4615-5901-6 (eBook) DOI 10.1007/978-1-4615-5901-6 This series is a continuat ion of the journal Sub-Cel/ular Biochemistry, Volumes 1 to 4 of which were published quarterly from 1972 to 1975 © 1997 Springer Science+Business Media New York Originally published by Plenum Press in 1997 Softcover reprint of the hardcover 1st edition 1997

All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher

INTERNATIONAL ADVISORY EDITORIAL BOARD J. L. AVILA, Instituto de Biomedicina, Caracas, Venezuela R. BITTMAN, Queens College of The City University of New York, Flushing, New York, USA N. BORGESE, CNR Center for Cytopharmacology, University of Milan, Milan, Italy D. DASGUPTA, Saha Institute of Nuclear Physics, Calcutta, India H. ENGELHARD