Comparative Genome Analyses
The extraordinary achievements of genome-based biology in recent years can be explained for the most part by the technological progress in DNA sequencing as well as developments in hardware and software that have made it possible to store and annotate hug
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Applied Bioinformatics An Introduction Second Edition
Including Exercises and Solutions
Applied Bioinformatics
Paul M. Selzer Richard J. Marhöfer Oliver Koch
Applied Bioinformatics An Introduction Second Edition
Paul M. Selzer Boehringer Ingelheim Animal Health Ingelheim am Rhein, Germany
Richard J. Marhöfer MSD Animal Health Innovation GmbH Schwabenheim, Germany
Oliver Koch TU Dortmund University Faculty of Chemistry and Chemical Biology Dortmund, Germany
The first edition of this textbook was written by Paul M. Selzer, Richard J. Marhöfer, and Andreas Rohwer Originally published in German with the title: Angewandte Bioinformatik 2018 ISBN 978-3-319-68299-0 ISBN 978-3-319-68301-0 (eBook) https://doi.org/10.1007/978-3-319-68301-0 Library of Congress Control Number: 2018930594 © Springer International Publishing AG, part of Springer Nature 2008, 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by the registered company Springer International Publishing AG part of Springer Nature The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
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Preface Though a relatively young discipline, bioinformatics is finding increasing importance in many life science disciplines, including biology, biochemistry, medicine, and chemistry. Since its beginnings in the late 1980s, the success of bioinformatics has been associated with rapid developments in computer science, not least in the relevant hardware and software. In addition, biotechnological advances, such as have been witnessed in the fields of genome sequencing, microarrays, and proteomics, have contributed enormously to the bioinformatics boom. Finally, the simultaneous breakthrough and success of the World Wide Web has facilitated the worldwide distribution of and easy access to bioinformatics tools. Today, bioinformatic
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