Comparison of visual field progression in new-diagnosed primary open-angle and exfoliation glaucoma patients in Sweden
- PDF / 538,255 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 18 Downloads / 164 Views
RESEARCH ARTICLE
Open Access
Comparison of visual field progression in new-diagnosed primary open-angle and exfoliation glaucoma patients in Sweden Marcelo Ayala
Abstract Background: The present study aimed to compare visual field progression in new-diagnosed exfoliation versus open-angle glaucoma patients. Methods: Retrospective study. The study included patients with new-diagnosed primary open-angle and exfoliation glaucoma. All patients were followed for 3 years with reliable visual fields. At least five reliable fields were needed for inclusion. Exfoliation and open-angle glaucoma were defined based on the European Glaucoma Society guidelines. Visual field evaluation was performed using the software threshold 24–2 of the Humphrey Field Analysis. Outcomes: Visual field progression. For visual field progression, three different strategies were used: mean deviation (MD), visual field index (VFI), and the guided progression analysis (GPA). Results: The study included 128 subjects, of the 54 in the open-angle and 74 in the exfoliation glaucoma group. The MD difference values were higher in the exfoliation (− 3.17 dB) than in the primary open-angle (− 1.25 dB) glaucoma group in the three-year follow-up period. The difference between groups was significant (t-test, p = < 0.001). The difference in VFI was calculated for the 3 years follow-up period. The difference was higher in the exfoliation (− 7.65%) than in the primary open (− 1.90%) glaucoma group (t-test, p = < 0.001). The GPA showed progression in 58% of cases in exfoliation, and 13% in primary open glaucoma group (Chi-square, p = < 0.001). Conclusion: The present study found a more frequent and faster visual field progression in exfoliation than in primary open-angle glaucoma patients. New-diagnosed exfoliation glaucoma patients must be controlled and treated more strictly than primary open-angle glaucoma patients to avoid visual field deterioration. Keywords: Exfoliation glaucoma, Visual field progression, Open-angle glaucoma, Sweden
Background Glaucoma is an optic neuropathy that can lead to blindness. It’s one of the most common causes of blindness in western countries [1]. Loss of ganglion cells with a consequent loss of visual field characterized the disease. Until now, no treatment has been discovered to cure the disease, and its character is progressive. Still, the cause of glaucoma is unknown, but several risk factors have Correspondence: [email protected]; [email protected] Eye Department, Skaraborg Hospital, Skövde, Sahlgrenska Academy, Gothenburg University & Karolinska Institute, 541 85 Skövde, Sweden
been described. Increased intraocular pressure (IOP) is the most common risk factor [2]. There are different types of glaucoma; among them, the two most common in Scandinavia are primary open-angle (POAG) and exfoliation glaucoma (EXFG) [3]. Primary open-angle glaucoma (POAG) can be defined as a progressive optic nerve disease that can lead to deterioration of visual field [4]. These changes are usually associated with increased IOP. The term
Data Loading...
