Effects of exercise and diet-induced weight loss on markers of inflammation I: impact on body composition and markers of

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POSTER PRESENTATION

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Effects of exercise and diet-induced weight loss on markers of inflammation I: impact on body composition and markers of health and fitness K Levers*, S Simbo, B Lockard, C Baetge, E Galvan, M Byrd, YP Jung, A Jagim, JM Oliver, M Koozehchian, R Dalton, D Khanna, B Sanchez, JY Kresta, K Horrell, T Leopold, M Cho, S Springer, A Rivera, C Cerda, C Rasmussen, R Kreider From International Society of Sports Nutrition: 10th Annual ISSN Conference and Expo Colorado Springs, CO, USA. 14-15 June 2013 Background The purpose of this study was to determine the effects of participating in a resistance-exercise based circuit training program while adhering to a higher protein diet designed to preserve fat free mass (FFM) during weight loss on body composition and markers of health. Then, in a companion paper, determine if exercise and diet-induced weight loss affect markers of inflammation. Methods 48 sedentary women (48.2±10.5 yr, 45.9±4.4% body fat, 35.6±5.6kg/m 2 ) were randomized to participate in the Curves® weight loss and exercise program (EX, n=28) or control group (C, n=20) for 12-wks. Participants followed an energy-restricted diet (1,200 kcal/d for 1-week and 1,500 kcal/d for 11 weeks; 30% CHO, 45% P, and 25% F) while participating in a circuit resistance-training (4 d/ wk) program. On one of the four exercise days, Zumba® dance was interspersed with the circuit resistance stations, wherein participants completed 60 seconds of resistance exercise followed by 60 seconds of dance. On the other three days of the 4 d/wk program, the workout included 30 seconds of resistance-exercise interspersed with 30 seconds of continuous movement (calisthenics, dance, etc.). DEXA body composition and fasting blood samples were obtained at 0 and 12-wks and analyzed by MANOVA. Data are presented as changes from baseline after 12-wks for the EX and C groups.

Results Overall MANOVA analysis revealed a significant group x time effect (p=0.004) for body composition measures. Univariate analysis revealed that participants in the EX group experienced greater changes in body weight (EX -4.0±4.4 kg; C 0.1±3.0 kg, p=0.001), fat mass (EX -3.8±4.0 kg; C -0.03±2.0 kg, p

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