Effects of Exercise on Hypertension From Cells to Physiological Syst

This text explores the state-of-the-art effects of exercise on blood pressure among adults with hypertension in addition to many of the possible mechanisms underlying essential hypertension in humans. The book contains chapters by distinguished experts on

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Linda S. Pescatello Editor

Effects of Exercise on Hypertension From Cells to Physiological Systems

Molecular and Translational Medicine

Series Editors William B. Coleman Gregory J. Tsongalis

More information about this series at http://www.springer.com/series/8176

Linda S. Pescatello Editor

Effects of Exercise on Hypertension From Cells to Physiological Systems

Editor Linda S. Pescatello Department of Kinesiology College of Agriculture Health, and Natural Resources University of Connecticut Storrs, CT, USA

ISSN 2197-7852 ISSN 2197-7860 (electronic) Molecular and Translational Medicine ISBN 978-3-319-17075-6 ISBN 978-3-319-17076-3 DOI 10.1007/978-3-319-17076-3

(eBook)

Library of Congress Control Number: 2015939172 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Humana Press is a brand of Springer Springer Science+Business Media LLC New York is part of Springer Science+Business Media (www. springer.com)

Foreword

During bouts of acute exercise, blood pressure rises. Paradoxically, high levels of chronic physical activity and aerobic exercise training can prevent some of the ageassociated rise in blood pressure seen in many normal humans, and exercise training can also lower blood pressure in those with hypertension. The rise in blood pressure with acute exercise is driven via neural signals known as central command acting in concert with baroreceptor resetting and feedback from skeletal muscle afferents. Together, these signals reduce the activity of the parasympathetic nervous system and increase the activity of the sympathetic nervous system. These adjustments cause the increase in heart rate and ultimately cardiac output, and also vasoconstriction in many vascular beds. The targets of these neural adjustments also offer clues about the long-protective effects of physical activity and exercise training on blood pressure. Likewise th