From Hypertension to Heart Failure

Arterial hypertension, coronary heart disease and heart fail­ ure are the commonest cardiovascular conditions to present in clinical practice. Over the past few years it has become in­ creasingly clear that they are closely and causally interrelated and t

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Springer Berlin Heidelberg New York Barcelona Budapest Hong Kong London Milan Paris Santa Clara Singapore Tokyo

M. Bohm

J. H.

Laragh

M. Zehender (Eds.)

From Hypertension to Heart Failure With 36 Figures

Springer

Professor Dr. med. MICHAEL BaHM Klinik III fur Innere Medizin der UniversWit Kaln Josef-Stelzmann-StraBe 9, 50924 Kaln, Germany Professor JOHN H. LARAGH The New York Hospital, Cornell Medical Center 526 East 68th Street, New York, NY 10021, USA Priv.-Doz. Dr. med. MANFRED ZEHENDER Med. Universitatsklinik und Poliklinik Abteilung Innere Medizin III HugstetterstraBe 55, 79106 Freiburg, Germany

ISBN-13:978-3-540-63542-0 Springer-Verlag Berlin Heidelberg New York Die Deutsche Bibliothek - CIP-Einheitsaufnahme From hypertension to heart failure/M. Bohm ... (ed.). - Berlin; Heidelberg; New York; Barcelona; Budapest; Hong Kong; London; Milan; Paris; Santa Clara; Singapore; Tokyo: Springer, 1998 ISBN-13:978-3-540-63542-0 DO!: 10.1007/978-3-642-60300-6

e-ISBN-13:978-3-642-60300-6

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Springer-Verlag Berlin· Heidelberg 1998

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Preface

Arterial hypertension, coronary heart disease and heart failure are the commonest cardiovascular conditions to present in clinical practice. Over the past few years it has become increasingly clear that they are closely and causally interrelated and that their relationship can have a significant bearing on prognosis. Epidemiological studies have shown that arterial hypertension is one of the most important risk factors for developing heart failure. Only one in four patients with hypertension is adequately managed, and in 50% of cases, the hypertension has not been recognised or treated. Patients with pre-existing hypertension who go on to suffer an acute myocardial infarction have usually not previously had typical angina symptoms, the infarct territory is larger, life threatening arrhythmias are commoner and hence in-hospital mortality and long-term prognosis are markedly worse. The presence of raised blood pressure in the post-infarct phase doubles the risk of manifest hear