Endocrine Pathology: Differential Diagnosis and Molecular Advances
Endocrine Pathology: Differential Diagnosis and Molecular Advances, Second Edition provides detailed coverage of endocrine pathology with extensive discussion of the differential diagnosis as well as presentation of molecular pathobiology of the major end
- PDF / 51,629,141 Bytes
- 602 Pages / 595.276 x 790.866 pts Page_size
- 27 Downloads / 222 Views
Ricardo V. Lloyd Editor
Endocrine Pathology Differential Diagnosis and Molecular Advances
Editor Ricardo V. Lloyd Department of Laboratory Medicine and Pathology Mayo Clinic Rochester, MN USA [email protected]
ISBN 978-1-4419-1068-4 e-ISBN 978-1-4419-1069-1 DOI 10.1007/978-1-4419-1069-1 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2009930630 © Springer Science+Business Media, LLC 2010 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface to Second Edition
The second edition of this book attempts to capture the rapid developments in molecular advances in endocrine pathology that have occurred in the past few years. This second edition continues the practice of utilizing the same general approach used by diagnostic pathologists as they examine endocrine lesions. Differential diagnoses based on the gross and histopathologic aspects of the lesions continues to be emphasized. The field of endocrine pathology remains in rapid transition. The chapters in this book attempt to capture these dynamic changes by discussing the basic approach to diagnosing endocrine lesions in addition to examining the most significant developments in cell and molecular biology that help to understand the pathophysiology of disease processes. Many of these new observations will soon make their way to the diagnostic bench of the pathologist who now utilizes many immunohistochemical stains and a few molecular tools in establishing specific diagnoses of endocrine lesions. These new approaches are especially helpful when the pathologist receives a small biopsy with a few millimeters of tissues from a fine needle aspiration biopsy procedure. The first chapter of this new edition is markedly expanded in attempts to capture most of the basic technical advances that have occurred in the past 5 years. An appreciation of the technical basis of these procedures provides insights for the critical evaluation of data generated with these techniques that the reader will encounter in the subsequent chapters. New chapters providing more in depth examination of the endocrine thymus, endocrine lung, skin and placenta, as well as molecular developments in the analysis of pheochromocytomas and paragangliomas have been added. The importance of the med
