Surgical Pathology of Endocrine and Neuroendocrine Tumors
Surgical pathology is the cornerstone in the management of neoplastic disorders. Written for the practicing surgical pathologist in mind, Surgical Pathology of Endocrine and Neuroendocrine Tumors provides an up-to-date text on surgical pathology of endocr
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CURRENT CLINICAL PATHOLOGY ANTONIO GIORDANO, MD, PHD SERIES EDITOR
For further titles published in this series, go to http://www.springer.com/springer/series/7632
SURGICAL PATHOLOGY OF E NDOCRINE AND NEUROENDOCRINE TUMORS
Edited by
ASHRAF KHAN, MD, FRCPath University of Massachusetts Medical School, Worcester, MA, USA
Editor Ashraf Khan Department Pathology University of Massachusetts Medical School (UMMS) UMassMemorial Medical Center 55 Lake Avenue N. Worcester MA 01655 USA
ISBN 978-1-60327-395-4 DOI 10.1007/978-1-60327-396-1
e-ISBN 978-1-60327-396-1
Library of Congress Control Number: 2009928457 #Humana Press, a part of Springer ScienceþBusiness Media, LLC 2009 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer ScienceþBusiness Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer ScienceþBusiness Media (www.springer.com)
To Rabab (Neelo) my loving wife, a great friend, the most caring person in the world and our two beautiful children Zehra and Faraan
PREFACE Surgical pathology is the cornerstone in management of neoplastic disorders. With the advances made in our understanding of disease and application of new ancillary diagnostic studies the cross talk between surgical pathology and its related fields such as cytopathology and molecular diagnosis has become important for patient care and to provide the most accurate diagnosis. Endocrine tumors are common surgical specimens that pathologists encounter in their practice, so the text presented here should be useful for most general pathologists and pathologists in training. In addition to the tumors of the usual endocrine glands we have included endocrine tumors of nonendocrine organs as well. As is discussed later by Dr. Runjan Chetty this system of specialized peptide producing cells that are distributed in various organs throughout the body share many properties with nerve cells; so for this group of tumors the terminology ‘‘neuroendocrine tumors’’ is preferred in this book. While the emphasis in this book is on the surgical pathology
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