Endocrinology of the Heart

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Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong

Prof. Dr. W. Kaufmann Prof. Dr. G. Wambach Medizinische Klinik II und Poliklinik der Universitat Ostmerheimer StraBe 200 D-5000 K61n 91

ISBN-13 :978-3-540-51409-1

DOl: 10.1007/978-3-642-83858-3

e- ISBN-13 :978-3-642-83858-3

Library of Congress Cataloging-in-Publication Data Endocrinology of the heart! editors, W. Kaufmann and G. Wambach. p. cm. Articles chiefly in English; 2 articles in German. Includes bibliographical references. ISBN-13:978-3-540-51409-1 (U.S.) 1. Atrial natriuretic peptides- Physiological effect. 2. HeartPhysiology. 3. Heart-Pathophysiology. 4. Endocrine glandsDiseases-Complications and sequelae. I. Kaufmann, Werner, 1924II. Wambch, G. [DNLM: 1. Heart-physiology. 2. Heart Diseases-physiopathology. 3. Natriuretic Peptides, Atrial. WG 202 E56] QP572.A82E53 1989 616.1'7-dc20 DNLMlDLC for Library of Congress

89-21677 CIP

This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, r"use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. Under § 54 of the German Copyright Law, where copies are made for other than private use, a fee is payable to Verwertungsgesellschaft Wort, Munich. © Springer-Verlag Berlin Heidelberg 1989

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2127/3335-543210

Table of Contents Author's Adresses . . . . . . . . . . . . . W .. Kaufmann, G. Wambach: Introduction

IX 1

Atrial Natriuretic Peptide: Morphology and Physiology

W. G. Forssmann, S. Feller, M. Meyer, P. Schulz-Knappe: Morphology of the Myoendrocine Cardiac Cell and Extra-Auricular Systems Producing Cardiac Hormones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . M. Gagelmann, S. Feller, D. Hock, P. Schulz-Knappe, W. G. Forssmann: Biochemistry ofthe Differential Release, Processing and Degradation of Cardiac and Related Peptide Hormones . . . . . . . . . . . . . . . . . . . . . . . . . H. Sonnenberg: Intrarenal Mechanism of Action of Atrial Natriuretic Factor T. Inagami, R. Takayanagi, K. N. Pandey, R. M. Snajdar, J. D. Corbin, S. H. Francis: Mechanism of Action of Atrial Natriuretic Factor in the Adrenal Gland . . . . G. Wambach: Atrial Natriuretic Peptide and the Renin-Angiotensin-AldosteroneSystem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . J. Holtz: Interaction between ANP and the Sympathetic Activity . . . . . . . . . D. J. Ramsay, C. H. Metzler,D. A. Scheuer, T. N. Thrasher: AtrialP