Environmental Radiation Effects on Mammals A Dynamical Modeling Appr
Dr. Smirnova's updated text is devoted to the theoretical studies of radiation effects on mammals. It summarizes 35 years of results the author obtained from analyzing dose rate equivalents for the Galactic Cosmic Rays (GCR) and for Solar Particles Events
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Environmental Radiation Effects on Mammals A Dynamical Modeling Approach Second Edition
Environmental Radiation Effects on Mammals
Olga A. Smirnova
Environmental Radiation Effects on Mammals A Dynamical Modeling Approach Second Edition
123
Olga A. Smirnova Research and Technical Center of Radiation-Chemical Safety and Hygiene, Moscow, Russian Federation
ISBN 978-3-319-45759-8 DOI 10.1007/978-3-319-45761-1
ISBN 978-3-319-45761-1 (eBook)
Library of Congress Control Number: 2016951310 © Springer International Publishing Switzerland 2010, 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Dedicated to my mother and father, Inna Mikhailovna Smirnova and Andrey Grigorievich Smirnov
Preface
The monograph presents the biologically motivated dynamic modeling approach to the study and prediction of radiation effects on mammals. This approach embodies the author’s mathematical models, which are capable of predicting the dynamics of vital body systems in mammals (namely, the hematopoietic system in rodents and humans, the immune system in rodents, the small intestine in rodents, and the skin in young swine) under normal conditions and under various irradiation regimes (acute/chronic/fractionated/non-uniform irradiation). The developed approach also includes the author’s mathematical models, which are capable of prognosticating the mortality dynamics and the average life-span shortening for homogeneous and nonhomogeneous (in radiosensitivity) mammalian populations exposed to acute and chronic irradiation in wide ranges of doses and dose rates on the basis of the statistical characteristics and the modeling dynamics of the respective critical body system (the hematopoietic system or the small intestine) in exposed specimens composing the population. The de
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