Fabrication of Ag NPs/Zn-MOF Nanocomposites and Their Application as Antibacterial Agents
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Fabrication of Ag NPs/Zn-MOF Nanocomposites and Their Application as Antibacterial Agents Reza Sacourbaravi1 · Zeinab Ansari‑Asl1 · Mohammad Kooti1 · Valiollah Nobakht1 · Esmaeil Darabpour2 Received: 27 March 2020 / Revised: 19 May 2020 / Accepted: 20 May 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Three new nanocomposites consisting of Zn(II) metal–organic framework (Zn-MOF) and Ag nanoparticles (Ag NPs), designated as Ag NPs/Zn-MOFs 1–3, based on the used doses of A gNO3, were fabricated. FT-IR (Fourier-transform infrared), PXRD (powder X-ray diffraction), SEM (scanning electron microscope), EDS (energy-dispersive X-ray spectroscopy) mapping, and TEM (transmission electron microscope) techniques were used for characterization of the prepared compounds. The obtained results have shown that the Ag NPs were successfully loaded on the Zn-MOF template. The spherical morphology of Ag NPs with diameter of 30–60 nm was confirmed through TEM analysis. The antibacterial activity of the synthesized compounds was then assessed against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, and Escherichia coli, using disc diffusion method. Among the studied composites, the one with higher dose of used A gNO3, i.e. Ag NPs/ Zn-MOF 1, had a broad-spectrum of antibacterial activity. Keywords Silver nanoparticles · Metal–organic Framework · Nanocomposite · Antibacterial activity
1 Introduction Metal nanoparticles have attracted a lot of interest and have been widely used in industrial, biological, and agricultural fields due to their unique electrical, optical, catalytic, and biological properties [1–3]. Among various metal nanoparticles, silver nanoparticles (Ag NPs) owing to their fascinating features have attracted much attention for their potential applications in various areas, including sensing materials, biomedical devices, and wound dressings [4–6]. Furthermore, due to their cytotoxic effect against various bacteria, Ag NPs can be considered as suitable antibacterial agent [7–9]. However, aggregation of Ag NPs in solution and the difficulty of their recovery are considered as two of the critical challenges for the wide applications of these nanoparticles. Therefore, many strategies were used for overcoming these problems, among them encapsulation and immobilization * Zeinab Ansari‑Asl [email protected] 1
Department of Chemistry, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran
Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran
2
of Ag NPs into/on various matrices were found to be more desired approaches [10–12]. On the other hand, metal–organic frameworks (MOFs), as porous organic–inorganic hybrids, have been widely applied as templates for immobilization of metal NPs [13–15]. MOFs are crystalline compounds consisting of metal ions and organic linkers. These structures, owing to their interesting properties, such as high porosity, high surface area, and diversity, have attracted much attention. The
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