Flucytosine Combined with Amphotericin B for Fungal Infections: A Postmarketing Surveillance and Future Perspectives
The incidence of fungal infections depends on the population studied. In immunodepressed patients and critically ill patients, fungal infections are emerging [1 , 2 ]. The clinical course is frequently complicated and prolonged, despite treatment. Treatme
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2008 Yearbook of Intensive Care and Emergency Medicine Edited by J.-L.Vincent
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Yearbook of Intensive Care and Emergency Medicine Edited by J.-L. Vincent
2008
Yearbook of Intensive Care and Emergency Medicine 2008 Edited by J.-L. Vincent
With 238 Figures and 90 Tables
Prof. Jean-Louis Vincent Head, Department of Intensive Care Erasme Hospital, Universit´e libre de Bruxelles Route de Lennik 808, B-1070 Brussels, Belgium
ISBN 978-3-540-77289-7 Springer-Verlag Berlin Heidelberg New York ISSN 0942-5381 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. Springer is a part of Springer Science+Business Media springer.com Springer-Verlag Berlin Heidelberg 2008 Printed in Germany The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about the application of operative techniques and medications contained in this book. In every individual case the user must check such information by consulting the relevant literature. Typesetting: FotoSatz Pfeifer GmbH, D-82166 Gräfelfing Printing: Stürtz GmbH, D-97080 Würzburg 21/3150 – 5 4 3 2 1 0 – Printed on acid-free paper
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Table of Contents
I Genetic Factors Are Pharmacogenetics and Pharmacogenomics Important for Critically Ill Patients? C. Kirwan, I. MacPhee, and B. Philips . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Genetic Susceptibility in ALI/ARDS: What have we Learned? R. Cartin-Ceba, M.N. Gong, and O. Gajic . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Racial Disparities in Infection and Sepsis: Does Biology Matter? F.B. Mayr, S. Yende, and D.C. Angus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
II Cardiac Issues B-type Natriuretic Peptide: An Emerging Biomarker in Pediatric Critical Care P.E. Oishi, J.-H. Hsu, and J.R. Fineman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 Cardiac Dysfunction in Septic Shock I. Cinel, R. Nanda, and R.P. Dellinger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 The Consequences of Cardiac Autonomic Dysfunction in Multiple Organ Dysfunction Syndrome H. Schmidt, U. Müller-Werdan, and K. Werdan . . . . . . . . . . . . . . . . . . . . . 55 Quantification of Improved Left Ventricular Performance during Cardiac Resyn
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