Hypertension and Heart Failure Epidemiology, Mechanisms and Trea

This book explains how hypertension affects 20-50% of the adult population in developed countries. Heart failure is the result of the hypertension's effects on the heart and it represents a growing public health problem.  In this context the internat

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Maria Dorobantu · Giuseppe Mancia  Guido Grassi · Victor Voicu Editors

Hypertension and Heart Failure Epidemiology, Mechanisms and Treatment

Updates in Hypertension and Cardiovascular Protection Series Editors Giuseppe Mancia Milano, Italy Enrico Agabiti Rosei Brescia, Italy

The aim of this series is to provide informative updates on both the knowledge and the clinical management of a disease that, if uncontrolled, can very seriously damage the human body and is still among the leading causes of death worldwide. Although hypertension is associated mainly with cardiovascular, endocrine, and renal disorders, it is highly relevant to a wide range of medical specialties and fields – from family medicine to physiology, genetics, and pharmacology. The topics addressed by volumes in the series Updates in Hypertension and Cardiovascular Protection have been selected for their broad significance and will be of interest to all who are involved with this disease, whether residents, fellows, practitioners, or researchers. More information about this series at http://www.springer.com/series/15049

Maria Dorobantu  ·  Giuseppe Mancia Guido Grassi  ·  Victor Voicu Editors

Hypertension and Heart Failure Epidemiology, Mechanisms and Treatment

Editors Maria Dorobantu Carol Davila University of Medicine and Pharmacy Bucharest and Cardiology Department Emergency Clinical Hospital Bucharest Romania Guido Grassi University of Milano-Bicocca Milano Italy

Giuseppe Mancia University of Milano-Bicocca Milano Italy Victor Voicu Department of Pharmacology Toxicology and Clinical Psychopharmacology Faculty of Medicine Carol Davila University of Medicine and Pharmacy Bucharest Romania

ISSN 2366-4606     ISSN 2366-4614 (electronic) Updates in Hypertension and Cardiovascular Protection ISBN 978-3-319-93319-1    ISBN 978-3-319-93320-7 (eBook) https://doi.org/10.1007/978-3-319-93320-7 Library of Congress Control Number: 2019931030 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that m