ACEi and ARBS in Hypertension and Heart Failure
This book summarizes how the renin angiotensin system is implicated in the progression of atherosclerotic disease as well as of left ventricular dysfunction and reviews the action of angiotensin converting enzyme inhibitors and AT1 receptor antagonists on
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Pasquale Perrone Filardi Editor
ACEi and ARBS in Hypertension and Heart Failure
Current Cardiovascular Therapy Series Editor Juan Carlos Kaski
More information about this series at http://www.springer.com/ series/10472
Pasquale Perrone Filardi Editor
ACEi and ARBS in Hypertension and Heart Failure
Editor Pasquale Perrone Filardi Cardiology School Federico II University of Naples Naples, Italy
ISBN 978-3-319-09787-9 ISBN 978-3-319-09788-6 (eBook) DOI 10.1007/978-3-319-09788-6 Springer Cham Heidelberg New York Dordrecht London Library of Congress Control Number: 2014951210 © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
The renin-angiotensin-aldosterone system has long been recognized to play a pivotal role in the pathogenesis of ischemic cardiovascular diseases and heart failure, and drugs that antagonize angiotensin II effects, namely ACE-inhibitors and AT1 receptor antagonists, are key in the therapy of patients affected by these conditions. These drugs have also demonstrated to reduce cardiovascular events in patients at high risk but without previous history of cardiovascular disease. This book, along the aims of the International Society of Cardiovascular Pharmacotherapy, provides a compr
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