Genetics of Male Infertility A Case-Based Guide for Clinicians
This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic a
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Genetics of Male Infertility
Mohamed Arafa • Haitham Elbardisi Ahmad Majzoub • Ashok Agarwal Editors
Genetics of Male Infertility A Case-Based Guide for Clinicians
Editors Mohamed Arafa Department of Urology Hamad Medical Corporation Doha, Qatar
Haitham Elbardisi Department of Urology Hamad Medical Corporation Doha, Qatar
Ahmad Majzoub Department of Urology Hamad Medical Corporation Doha, Qatar
Ashok Agarwal Cleveland Clinic Cleveland, OH USA
ISBN 978-3-030-37971-1 ISBN 978-3-030-37972-8 (eBook) https://doi.org/10.1007/978-3-030-37972-8 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Foreword
The treatment of male infertility is progressively changing. One of the areas where new knowledge could lead to impressive new therapeutic opportunities is in the area of genetics of male fertility. This book Genetics of Male Infertility is presented as a case-based discussion of conditions that may affect male fertility. The topics covered in the book are broad-ranging and relevant for the understanding of all conditions that are important for management of the infertile male. Each chapter has a broad overview of the subject matter, complete with literature search. Each chapter provides a structured topic discussion that is often emphasized with a case discussion, where the condition being overviewed is tied to a specific clinical scenario to enhance the clinical relevance of the chapter. Some topics are of general information that are of importance for a complete understanding of male reproductive function. For example, Chaps. 1, 4, 7, 17, 18, and 19 are critical chapters that provide key foundations of genetic factors that are involved in
