Handbook of Teratology Mechanisms and Pathogenesis
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Teratology
2
Mechanisms and Pathogenesis
Handbook of Teratology
Volume 1: General Principles and Etiology Volume 2:
Mechanisms and Pathogenesis
Volume 3:
Comparative, Maternal, and Epidemiologic Aspects
Volume 4:
Research Procedures and Data Analysis
Handbook of
Teratology Edited by
JAMES G. WILSON The Children's Hospital Research Foundation and Department of Pediatrics, University of Cincinnati Cincinnati, Ohio
and
F. CLARKE FRASER Departments of Biology and Paediatrics McGill University and The Montreal Children's Hospital Montreal, Canada
2
Mechanisms and Pathogenesis
PLENUM PRESS . NEW YORK AND LONDON
Library of Congress Cataloging in Publication Data Main entry under title: Handbook of teratology. Includes bibliographies and index. CONTENTS: v.1. General principles and etiology.-v. 2. Mechanisms and patho· genesis. 1. Abnormalities. 2. Teratogenic agents. I. Wilson, James Graves, 1915· II. Fraser, F. Clarke, 1920· [DNLM: 1. Abnormalities. QS675 H236] 616'.043 7641787 QM691.H26
ISBN-13: 978-1-4615-8935-8
e-ISBN-13: 978-1-4615-8933-4
001: 10.1007/978-1-4615-8933-4
© 1977 Plenum Press, New York
Softcover reprint of hardcover 2nd edition 1977
A Division of Plenum Publishing Corporation 227 West 17th Street, New York, N.Y. 10011 All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher
Contributors
G. J. BINGLE, Laboratory of Developmental Biology and Anomalies, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland ROBERT PAUL BOLANDE, Director of the Department of Pathology, The Montreal Children's Hospital, and Professor of Pathology and Paediatrics, McGill University, Montreal, Quebec, Canada ALFRED J. COULOMBRE, Laboratory of Vision Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland JANE L. COULOMBRE, Late of the Laboratory of Vision Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland F. CLARKE FRASER, Departments of Biology and Paediatrics, McGill University, and Director, Department of Medical Genetics, The Montreal Children's Hospital, Montreal, Quebec, Canada DAVID FROMSON, Department of Biology, McGill University, Montreal, Quebec, Canada SALOME GLUECKSOHN- WAELSCH, Department of Genetics, Albert Einstein College of Medicine, Bronx, New York ALLEN S. GOLDMAN, The Teratology Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania CASIMER T. GRABOWSKI, Department of Biology, University of Miami, Coral Gables, Florida KURT HIRSCHHORN, Department of Pediatrics, Division of Medical Genetics, Mount Sinai School of Medicine of the City University of New York, New York LILLIAN Y. F. HSU, Department of Pediatrics, Division of Medical Genetics, Mount Sinai School of Medicine of the City University of New York, New York OSCAR C. JAFFEE, Department of Biology, University of Dayt
