Hematopathology Advances in Understanding
This book covers recent advances in the understanding and management of essential hematological pathologies. In addition to updates on Hodgkin’s lymphoma, acute myeloid leukemia and other disorders, it provides essential information on transplant patholog
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Hematopathology
Renu Saxena • Hara Prasad Pati Editors
Hematopathology Advances in Understanding
Editors Renu Saxena Department of Hematology All India Institute of Medical Sciences New Delhi India
Hara Prasad Pati Department of Hematology All India Institute of Medical Sciences New Delhi India
ISBN 978-981-13-7712-9 ISBN 978-981-13-7713-6 (eBook) https://doi.org/10.1007/978-981-13-7713-6 © Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Contents
Part I Red Cell Disorders 1 Newer CBC Parameters of Clinical Significance�������������������������� 3 Shanaz Khodaiji 2 Iron Metabolism and Iron Deficiency Anemia������������������������������ 27 Meera Sikka and Harresh B. Kumar 3 Megaloblastic Anemia and Dual Nutritional Deficiency Anemia���������������������������������������������������������������������������������������������� 49 K. V. Karthika and Hara Prasad Pati 4 Pathogenesis and Investigations in Hereditary Red Blood Cell Membrane Disorders���������������������������������������������������� 59 Monica Sharma 5 Molecular Genetics of Inherited Red Cell Membrane Disorders������������������������������������������������������������������������������������������ 77 Anu Aggarwal, Manu Jamwal, and Reena Das 6 Historical Investigations and Advances in Flow Cytometry-Based Tests in Paroxysmal Nocturnal Hemoglobinuria������������������������������������������������������������������������������� 91 Khaliqur Rahman and Dinesh Chandra 7 Laboratory Diagnosis of Microangiopathic Hemolytic Anemia Including TTP, DIC, and HUS ���������������������������������������� 109 Aakanksha Singh and Mrinal
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