Hepatitis C Virus Replication

Viruses use synthetic mechanism and organelles of the host cells to facilitate their replication and make new viruses. Host’s ATP provides necessary energy. Hepatitis C virus (HCV) is a major cause of liver disease. Like other positive-strand RNA viruses,

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Mitsuo Tagaya Thomas Simmen Editors

Organelle Contact Sites From Molecular Mechanism to Disease

Advances in Experimental Medicine and Biology Volume 997 Editorial Board Irun R. Cohen, The Weizmann Institute of Science, Rehovot, Israel Abel Lajtha, N.S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA John D. Lambris, University of Pennsylvania, Philadelphia, PA, USA Rodolfo Paoletti, University of Milan, Milan, Italy

Advances in Experimental Medicine and Biology presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents offers readers multiple perspectives on a variety of disciplines including neuroscience, microbiology, immunology, biochemistry, biomedical engineering and cancer research. Advances in Experimental Medicine and Biology has been publishing exceptional works in the field for over 30 years and is indexed in Medline, Scopus, EMBASE, BIOSIS, Biological Abstracts, CSA, Biological Sciences and Living Resources (ASFA-1), and Biological Sciences. The series also provides scientists with up to date information on emerging topics and techniques. 2015 Impact Factor: 1.953 More information about this series at http://www.springer.com/series/5584

Mitsuo Tagaya • Thomas Simmen Editors

Organelle Contact Sites From Molecular Mechanism to Disease

Editors Mitsuo Tagaya School of Life Sciences Tokyo University of Pharmacy and Life Sciences Hachioji, Tokyo, Japan

Thomas Simmen Department of Cell Biology University of Alberta Edmonton, Alberta, Canada

ISSN 0065-2598 ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-981-10-4566-0 ISBN 978-981-10-4567-7 (eBook) DOI 10.1007/978-981-10-4567-7 Library of Congress Control Number: 2017947694 # Springer Nature Singapore Pte Ltd. 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. P

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