High prevalence of hepatitis A in indigenous population in north Brazil

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(2020) 13:458 de Paula et al. BMC Res Notes https://doi.org/10.1186/s13104-020-05303-y

Open Access

RESEARCH NOTE

High prevalence of hepatitis A in indigenous population in north Brazil Vanessa Salete de Paula1, Flavio Augusto Pádua Milagres2, Guilherme de Macêdo Oliveira3, Juliana Custódio Miguel4, Helena Medina Cruz4, Leticia de Paula Scalioni4,5, Vanessa Alves Marques4, Monica de Avelar Figueiredo Mafra Magalhães6, Anselmo Rocha Romão6, Renata Gracie6 and Livia Melo Villar4* 

Abstract  Objectives:  Little is known about hepatitis A virus (HAV) prevalence in indigenous communities. This study aims to evaluate the prevalence of HAV in indigenous community compared to urban population located at Western Amazon in Brazil. Results:  A total of 872 serum samples were obtained from 491 indigenous and 381 non indigenous individuals aging 0 to 90 years. Samples were tested for total and IgM anti-HAV and positive IgM samples were tested for HAV RNA. The overall prevalence of total anti-HAV was 87%, increased according age showing 100% of prevalence in those aging more than 30 years (p