High prevalence of human papillomavirus type 66 in low-grade cervical lesions of Mexican women
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BRIEF REPORT
High prevalence of human papillomavirus type 66 in low‑grade cervical lesions of Mexican women Karina Juárez‑González1 · Vladimir Paredes‑Cervantes2 · Silvia Gordillo‑Rodríguez3 · Saul González‑Guzmán4,5 · Xochilt Moncayo‑Valencia3 · Rocío Méndez‑Martínez6 · Alejandro García‑Carrancá7 · José Darío Martínez‑Ezquerro8 · Rodolfo Rivas‑Ruiz9 · Patricia Sánchez‑Suárez10 · Paola Álvarez‑Sandoval11 · Patricia Padilla‑Arrieta11 · Martha Martínez‑Salazar12 · Salvador Vázquez‑Vega13 Received: 2 March 2020 / Accepted: 7 July 2020 © Springer-Verlag GmbH Austria, part of Springer Nature 2020
Abstract Our aim was to analyze the prevalence of high-risk human papillomavirus (HR-HPV) and its association with risk factors related to cervical lesions. We used 362 cervical samples from a transversal study to detect nineteen types from the high-risk HPV clade by highly sensitive PCR. Unexpectedly, we found a very high prevalence of HPV type 66 (32.8%), particularly in low-grade squamous intraepithelial lesions. A significant association of HPV66 with previously sexually transmitted disease was observed (p
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