Hospital-acquired acute kidney injury in very elderly men: clinical characteristics and short-term outcomes
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ORIGINAL ARTICLE
Hospital‑acquired acute kidney injury in very elderly men: clinical characteristics and short‑term outcomes Qinglin Li1 · Meng Zhao2 · Feihu Zhou1 Received: 2 April 2018 / Accepted: 3 April 2019 © The Author(s) 2019
Abstract Objectives We explored the risk factors for, and the clinical characteristics of, acute kidney injury (AKI), and the causes of death 28 days after such injury, in very elderly men. Methods This was a retrospective cohort study using data from the Geriatric Department of the Chinese PLA General Hospital. A total of 3464 elderly patients (≥ 75 years) were enrolled from January 2007 to December 2015. All patients were followed for 28 days or until death after AKI. Results In total, 668 patients (39.0%) developed AKI, and 623 men were included for the final analysis. The median age was 87 years. The 28-day mortality rate was 25.7%. The AKI etiologies were infections (39.6%), hypovolemia (23.8%), cardiovascular events (15.9%), nephrotoxicity (12.0%), and surgery (7.1%). Multiple organ dysfunction syndrome (46.4%) and pulmonary infection (22.5%) were the principal causes of death. Multivariate analysis revealed that time for AKI to develop (HR = 0.865; 95% CI 0.799–0.937; P
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