How to Write a Successful Research Grant Application A Guide for Soc

How to Write a Successful Research Grant Application A Guide for Social and Behavioral Scientists, 2nd Edition By Willo Pequegnat, Ellen Stover, and Cheryl Boyce National Institute of Mental Health, Rockville, MD, USA Over the last fifty years behavioral

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HOW TO WRITE A SUCCESSFUL RESEARCH GRANT APPLICATION A Guide for Social and Behavioral Scientists Edited by

WILLO PEQUEGNAT AND ELLEN STOVER National Institute of Mental Health Rockville, Maryland

SPRINGER SCIENCE+BUSINESS MEDIA, LLC

L1brary of Congress Catalog1ng-1n-Publ1cat1on Data

How to write a successful research grant application a guide for social and behav1oral sc1ent1sts I edited by W1llo Pequegnat and Ellen Stover. p.

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Includes bibliographical references witz exam page appendix 15). b. Sensorimotor function during the first year of life will be tested using the neurologic evaluation developed by Amiel-Tison (35). Items testing sensation, standing and walking will be added. This evaluation will be sensitive to changes in tone and primitive reflexes that reflect sensorimotor dysfunction in children with HIV infections. This scale can also identify peripheral nerve and muscle dysfunction because of the hypotonia and decreased motor function in the latter. Each item is easily scored using the form developed by Amiel-Tison. Testing will be rescheduled if the infant is acutely ill and uncomfortable or agitated. Because a wide range of individual variations in tone are present in normal development, a persistent pattern of abnormality over serial examinations and present at one year must be present before the findings will be classified as abnormal. This pattern will allow us to identify the time of appearance of early changes in the sensorimotor examination as well as the identification of transient neuromotor abnormalities (AmielTison Exam appendix 16). The sensorimotor examination for the second year of life will encompass the following functional groups: Gross motor skills; Fine motor skills; Tone and posture; Involuntary movements; Sensory; and Cranial nerves. Right and left sided function will be separately scored. Each test will be scored as 0 = normal, 1 = mild-moderately abnormal, and 2 = severely abnormal (Toddler Neurologic Exam appendix 17) . The sensorimotor neurologic examination will be performed by the local medical officer in the project, who will be trained in the administration of the examination by a pediatric neurologist. Training will be done on the neurologist's initial visit to Uganda and will be verified on subsequent trips and by the neurologist's evaluation of videotaped examinations. Instructions on examination administration is available in publications by Dubowitz and Amiel-Tison, on a videotape of the infant and toddler exam and in a manual for the older child's exam. Independent scoring of the videotape and supervised exams will be done to enhance inter-observer reliability. Cross-cultural application of measures: The measures were chosen for their relative ease of administration, feasibility for use in the field, and potential transfer across cultures. The Fagan test is portable, can be adapted for field use by using a hand held recorder and has been utilized in home settings in several studies. The Fagan test assesses visual recognition memory, a function which can re