Identification of the subtypes of gastric cancer based on DNA methylation and the prediction of prognosis

  • PDF / 2,989,407 Bytes
  • 15 Pages / 595.276 x 790.866 pts Page_size
  • 23 Downloads / 200 Views

DOWNLOAD

REPORT


Open Access

RESEARCH

Identification of the subtypes of gastric cancer based on DNA methylation and the prediction of prognosis Tengda Li1  , Xin Chen2, Mingli Gu3, Anmei Deng4* and Cheng Qian5*

Abstract  Background:  Gastric cancer (GC) is a digestive system cancer with a high mortality rate globally. Previous experiences and studies have provided clinicians with ample evidence to diagnose and treat patients with reasonable therapeutic options. However, there remains a need for sensitive biomarkers that can provide clues for early diagnosis and prognosis assessment. Results:  We found 610 independent prognosis-related 5′-cytosine-phosphate-guanine-3′ (CpG) sites (P