Immuno Systems Biology A macroscopic approach for immune cell signal
Technological advances of modern biology have generated high volumes of ‘omics’ data. The natural precedence has been to put the complex information together, so that it will lead to spectacular scientific discoveries and medical breakthroughs. In this li
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Kumar Selvarajoo
Immuno Systems Biology A macroscopic approach for immune cell signaling
Systems Biology Volume 3
Series Editor Sangdun Choi
For further volumes: http://www.springer.com/series/7890
Kumar Selvarajoo
Immuno Systems Biology A macroscopic approach for immune cell signaling
Kumar Selvarajoo Institute for Advanced Biosciences Keio University Tsuruoka, Yamagata, Japan
ISSN 2191-222X ISSN 2191-2238 (electronic) ISBN 978-1-4614-7459-3 ISBN 978-1-4614-7690-0 (eBook) DOI 10.1007/978-1-4614-7690-0 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2013942972 © Springer Science+Business Media New York 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
Systems biology is an emerging field integrating traditional and modern biological techniques with systemic approaches adopted from physics, mathematics, engineering, and computer science. Immuno systems biology specifically aims to study the host immune system in a more integrated manner as to how different cells and molecules participate at system levels to invoke the global proinflammatory response to fight against intruders. In this book, I focus on the dynamic analyses of mammalian innate immune response to bacterial and viral perturbations using computati
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