Immunotherapy of Cancer An Innovative Treatment Comes of Age
This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy. Included are explanations of the constitution of the immune system and immunocheckpoints, the
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Immunotherapy of Cancer An Innovative Treatment Comes of Age
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Immunotherapy of Cancer
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Yoshiyuki Yamaguchi Editor
Immunotherapy of Cancer An Innovative Treatment Comes of Age
Editor Yoshiyuki Yamaguchi Department of Clinical Oncology Kawasaki Medical School Kurashiki, Japan
ISBN 978-4-431-55030-3 ISBN 978-4-431-55031-0 DOI 10.1007/978-4-431-55031-0
(eBook)
Library of Congress Control Number: 2015960813 Springer Tokyo Heidelberg New York Dordrecht London © Springer Japan 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer Japan KK is part of Springer Science+Business Media (www.springer.com)
Preface
Preparation of this book started in October 2013, when the 51st Annual Meeting of the Japan Society of Clinical Oncology (JSCO) was held in Kyoto, Japan. When the editorship was offered to me, I thought, Why me? I was too inexperienced to complete such a great book, with so many Japanese experts in this field. However, I decided to take on the challenge of producing the book with much help from my dedicated older and younger colleagues. Here, I want to express my sincere thanks to all the authors who contributed. This book contains the history, current status, and future perspective of cancer immunotherapy. The reader may understand easily, I hope, what you should know about the immune system when you treat a cancer patient. Immunotherapy has now come of age as the fourth modality of cancer treatment. Its role in cancer treatment, I believe, will grow day by day, and a future revolution in cancer treatment will occur as all the other treatments, including surgery, chemotherapy, and radiotherapy, may exist with and for the success of cancer immunotherapy. About 30 years ago, when I was still a young surgeon, I was absorbed in research for tumor immunology. My Ph.D. thesis was titled “An Analysis of Suppressor Factor–Receptors on Peripheral Blood Lymphocyte Surfaces of Cancer Patients”. My esteemed profes
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