In vivo Models of HIV Disease and Control

An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between HIV and immune deficiency infections in a variety of animals, it is only natural that scientists use these

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INFECTIOUS DISEASES AND PATHOGENESIS Series Editors: Mauro Bendinelli, University of Pisa Herman Friedman, University of South Florida College of Medicine Recent volumes in this series: IN VIVO MODELS OF HIV DISEASE AND CONTROL Edited by Herman Friedman, Steven Specter, and Mauro Bendinelli INFECTIOUS DISEASES AND SUBSTANCE ABUSE Edited by Herman Friedman, Catherine Newton, and Thomas W. Klein CHLAMYDIA PNEUMONIAE INFECTION AND DISEASE Edited by Herman Friedman, Yoshimasa Yamamoto, and Mauro Bendinelli DNA TUMOR VIRUSES Oncogenic Mechanisms Edited by Giuseppe Barbanti-Brodano, Mauro Bendinelli, and Herman Friedman ENTERIC INFECTIONS AND IMMUNITY Edited by Lois J. Paradise, Mauro Bendinelli, and Herman Friedman HELICOBACTER PYLORI INFECTION AND IMMUNITY Edited by Yoshimasa Yamamoto, Herman Friedman, and Paul S. Hoffman HERPES VIRUSES AND IMMUNITY Edited by Peter G. Medveczky, Herman Friedman, and Mauro Bendinelli HUMAN RETROVIRAL INFECTIONS Immunological and Therapeutic Control Edited by Kenneth E. Ugen, Mauro Bendinelli, and Herman Friedman MICROORGANISMS AND AUTOIMMUNE DISEASES Edited by Herman Friedman, Noel R. Rose, and Mauro Bendinelli OPPORTUNISTIC INTRACELLULAR BACTERIA AND IMMUNITY Edited by Lois J. Paradise, Herman Friedman, and Mauro Bendinelli A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information, please contact the publisher.

In vivo Models of HIV Disease and Control Edited by

Herman Friedman University of South Florida Tampa, FL, USA

Steven Specter University of South Florida Tampa, FL, USA

Mauro Bendinelli University of Pisa Pisa, Italy

Herman Friedman Department of Medical Microbiology and Immunology University of South Florida College of Medicine Tampa, FL 33612 USA

Steven Specter Department of Medical Microbiology and Immunology University of South Florida College of Medicine Tampa, FL 33612 USA

Mauro Bendinelli Department of Experimental Pathology and Retrovirus Center University of Pisa Via S. Zeno, 37 Pisa, I-56127 Italy

Library of Congress Control Number: 2005924712 ISBN-10: 0-387-25740-3 ISBN-13: 978-0387-25740-2

e-ISBN 0-387-25741-1

Printed on acid-free paper. © 2006 Springer Science+Business Media, Inc. All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, Inc., 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now know or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Pri