Inclusion of Lactobacillus salivarius strain revealed a positive effect on improving growth performance, fecal microbiot
- PDF / 1,264,105 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 0 Downloads / 179 Views
ORIGINAL PAPER
Inclusion of Lactobacillus salivarius strain revealed a positive effect on improving growth performance, fecal microbiota and immunological responses in chicken Shanmugam Sureshkumar1,2 · Hwi Cheul Lee1 · Sun Keun Jung1 · Dongjun Kim3 · Keon Bong Oh1 · Hyeon Yang1 · Yong Jin Jo1 · Hae Sun Lee1 · Sukchan Lee3 · Sung June Byun1 Received: 12 August 2020 / Revised: 23 September 2020 / Accepted: 6 October 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Probiotics are defined as live microorganisms that when administered in an appropriate amount, provide health benefits to the host. This study aimed to evaluate the effect of the oral administration of Lactobacillus salivarius (L. salivarius) on growth performance, immunological responses, fecal microbial flora and intestinal mucosal morphology in chickens. Chickens were fed with 109 colony-forming units (CFUs) of wild-type (WT) L. salivarius or phosphate-buffered saline (PBS) for 5 weeks. Chickens body weight was significantly increased by administration of L. salivarius groups compared than control group. The microbial taxonomy in the small intestine and cecum was identified via the chicken feces sample. A total of 286,331 bacterial species were obtained from the chicken fecal samples in overall experimental group. From these, 145,012 bacterial species were obtained from oral administration of L. salivarius treatment group, while 141,319 bacterial species were obtained from control group. Almost 98% of all 16S rRNA sequences from the chicken fecal sample of the two groups were classified into known phyla. Firmicutes, Cyanobacteria, Proteobacteria, Bacteroidetes and Actinobacteria were highly abundant in both groups. Compared with the control birds, the chickens orally administered L. salivarius showed no significant differences in villus length and crypt length. Serum concentrations of the cytokines IL-8, TNF-α, IFN-γ, and IL-4 were markedly reduced in the L. salivarius group. In summary, our findings reveal that L. salivarius can act as a potential probiotic to improve performance and overall gut health in of chickens. Keywords Lactobacillus salivarius · Chicken · Oral administration
Introduction Antibiotic growth promoters (AGP) have been commonly used in broiler chicken production to maintain health and improve efficiency. However, due to the development of Communicated by Erko Stackebrandt. * Sung June Byun [email protected] 1
Animal Biotechnology Division, National Institute of Animal Science, Rural Development Administration, 1500, Wanju‑gun 441‑706, Republic of Korea
2
Department of Animal Resource and Science, Dankook University, Cheonan‑si, Chungnam 31116, South Korea
3
Department of Integrative Biotechnology, Sungkyunkwan University, 2066, Seobu‑ro, Jangan‑gu, Suwon‑si, Gyeonggi‑do, Republic of Korea
microbe resistance to antibiotics used to treat human and animal infections, the European Union banned the use of AGP in poultry diets as of Jan 1st, 2006 (Nguyen et al. 2019). This has led researchers
Data Loading...
