Innovations in Molecular Mechanisms and Tissue Engineering
This book marries stem cell biology, tissue engineering, and regenerative biology into a single, interdisciplinary volume. The chapters also explore embryonic stem cells, induced pluripotent stem cells, cardiovascular regeneration, skeletal development, i
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Jeanne Wilson-Rawls Kenro Kusumi Editors
Innovations in Molecular Mechanisms and Tissue Engineering
Stem Cell Biology and Regenerative Medicine
Series Editor Kursad Turksen, Ph.D. [email protected]
More information about this series at http://www.springer.com/series/7896
Jeanne Wilson-Rawls • Kenro Kusumi Editors
Innovations in Molecular Mechanisms and Tissue Engineering
Editors Jeanne Wilson-Rawls School of Life Sciences Arizona State University Tempe, AZ, USA
Kenro Kusumi School of Life Sciences Arizona State University Tempe, AZ, USA Neurogenomics Division Translational Genomics Research Institute Phoenix, AZ, USA
ISSN 2196-8985 ISSN 2196-8993 (electronic) Stem Cell Biology and Regenerative Medicine ISBN 978-3-319-44994-4 ISBN 978-3-319-44996-8 (eBook) DOI 10.1007/978-3-319-44996-8 Library of Congress Control Number: 2016957175 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Interest in regeneration has waxed and waned since Lazzaro Spallanzani first described salamander limb regeneration in the eighteenth century. Currently, regeneration is a highly researched area with potential applications derived from biomedical and engineering research that will impact future medical therapies. The availability of genomic and transcriptomic data from regenerative species, combined with new approaches to identify and culture stem cells, has led to an explosive growth in our understanding of the molecular mechanisms of regeneration. In this book, we bring together the latest insights into these mechanisms. In the first chapter, Debuque and Godwin describe the history of molecular research in salamanders and discuss the latest findings on unique proteins that mediate regeneration. These aut
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