Investigating beam matching for multi-room pencil beam scanning proton therapy
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SCIENTIFIC PAPER
Investigating beam matching for multi‑room pencil beam scanning proton therapy Suresh Rana1,2,3 · Jaafar Bennouna1,2 Received: 29 March 2020 / Accepted: 10 September 2020 © Australasian College of Physical Scientists and Engineers in Medicine 2020
Abstract The purpose of this study was to investigate the proton beam matching for a multi-room ProteusPLUS pencil beam scanning (PBS) proton therapy system and quantify the agreement among three beam-matched treatment rooms (GTR1, GTR2, and GTR3). In-air spot size measurements were acquired using a 2D scintillation detector at various gantry angles. Range and absolute dose measurements were performed in water at gantry angle 0°. Patient-specific quality assurance (QA) plans of four different disease sites (brain, mediastinum, sacrum, and prostate) and machine QA fields with uniform dose were delivered for various beam conditions. The results from GTR1 were considered as reference values. The average difference in spot sizes between GTR2 and GTR1 was − 0.3% ± 2.2% (range, − 5.9 to 5.8%). For GTR3 vs. GTR1, the average difference in spot sizes was 0.6% ± 1.7% (range, − 4.8 to 4.6%). The spot symmetry was found to be ≤ 4.4%. For proton range, the difference among three rooms was within ± 0.5 mm. On average, the difference in absolute dose was − 0.1 ± 0.7% (range, − 1.3 to 2.1%) for GTR2 vs. GTR1 and 0.7 ± 0.6% (range, − 0.1 to 2.1%) for GTR3 vs. GTR1. The average gamma passing rate of patient-specific QA measurements (n = 29) was ≥ 98.6%. The average gamma passing rate of machine QA fields was 99.9%. In conclusion, proton beam matching was quantified for three beam-matched rooms of an IBA ProteusPLUS system with a PBS dedicated nozzle. It is feasible to match the spot size and absolute dose within ± 5% and ± 2%, respectively. Proton range can be matched within ± 0.5 mm. Keywords Beam-matching · Spot size · Range · Absolute dose · Pencil beam scanning · Proton therapy
Introduction Proton radiation beam matching among different treatment rooms provides the flexibility of transferring a patient from one matched room to another without the necessity of regenerating a treatment plan, especially when one of the beammatched rooms is down. A single proton beam model in the treatment planning system (TPS) can be shared among beammatched rooms. Another advantage of having beam-matched proton treatment rooms is the flexibility of performing * Suresh Rana [email protected]; [email protected] 1
Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Drive, Miami, FL 33176, USA
2
Department of Radiation Oncology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA
3
Department of Physics, School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, India
patient-specific quality assurance (QA) tasks in any given beam-matched room. Thus, the proton beam-matching option can potentially improve the efficiency of daily clinical workflow in a multi-room prot
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