Nanoscale Insights into Ion-Beam Cancer Therapy
This book provides a unique and comprehensive overview of state-of-the-art understanding of the molecular and nano-scale processes that play significant roles in ion-beam cancer therapy. It covers experimental design and methodology, and reviews the theor
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anoscale Insights into Ion-Beam Cancer Therapy
Nanoscale Insights into Ion-Beam Cancer Therapy
Andrey V. Solov’yov Editor
Nanoscale Insights into Ion-Beam Cancer Therapy
123
Editor Andrey V. Solov’yov MBN Research Center at Frankfurter Innovationszentrum Biotechnologie Frankfurt am Main Germany and A.F. Ioffe Physical-Technical Institute Saint Petersburg Russia
ISBN 978-3-319-43028-7 DOI 10.1007/978-3-319-43030-0
ISBN 978-3-319-43030-0
(eBook)
Library of Congress Control Number: 2016950401 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
This book provides a unique and comprehensive overview of state-of-the-art understanding of the molecular and nanoscale processes that play important roles in ion-beam cancer therapy. It covers experimental design and methodology, and reviews the theoretical understanding of the processes involved. It offers the reader an opportunity to learn from a coherent approach about the physics, chemistry and biology relevant to ion-beam cancer therapy, a growing field of important medical application worldwide. The book describes phenomena occurring on different time, spatial and energy scales relevant to the radiation damage of biological targets and ion-beam cancer therapy from the molecular (nano) scale up to the macroscopic level. It illustrates how ion-beam therapy offers the possibility of excellent dose localization for treatment of malignant tumours, minimizing radiation damage in normal tissue whilst maximizing cell-killing within the tumour, offering a significant development in cancer therapy. The full potential of such therapy can only be realized through the understanding of the physical, chemical and biological mechanisms, on a range of time and space s
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