Investigations of Early Nutrition Effects on Long-Term Health Method
This volume contains several reviews in the field as well as the step-by-step use of targeted and global approaches within the areas of genomics, epigenetics, proteomics, transcriptomics and metabolomics which aim to address this dilemma and to help pinpo
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Paul C. Guest Editor
Investigations of Early Nutrition Effects on LongTerm Health Methods and Applications
METHODS
IN
MOLECULAR BIOLOGY
Series Editor John M. Walker School of Life and Medical Sciences, University of Hertfordshire, Hatfield, Hertfordshire AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Investigations of Early Nutrition Effects on Long-Term Health Methods and Applications
Edited by
Paul C. Guest Debden, Essex, UK
Editor Paul C. Guest Debden, Essex, UK
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-7613-3 ISBN 978-1-4939-7614-0 (eBook) https://doi.org/10.1007/978-1-4939-7614-0 Library of Congress Control Number: 2017964007 © Springer Science+Business Media, LLC 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer Science+Business Media, LLC The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Preface Environmental factors such as suboptimal parental diet can lead to perturbations of in utero growth and development. In turn, this can have long-lasting negative effects on health in later life by leading to increased risk and earlier onset of diseases such as type 2 diabetes, obesity, cardiovascular conditions, cancer, and neurological disorders. In addition, future generations are at risk of inheriting these conditions through nongenetic mechanisms. Elucidating the molecular pathways involved in these processes may help in the design of prevention strategies and may also lead to the identification of biomarkers and potential drug targets for improved patient management. This book contains several reviews in the field as well as the step-by-step use of targeted and global approaches within the areas of genomics, epigenetics, p
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