Late-onset depression is associated to age-related central auditory processing disorder in an older population in Southe
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ORIGINAL ARTICLE
Late-onset depression is associated to age-related central auditory processing disorder in an older population in Southern Italy Madia Lozupone & Rodolfo Sardone & Rossella Donghia & Francesca D’Urso & Carla Piccininni & Petronilla Battista & Ilaria Di Gioia & Emanuela Resta & Fabio Castellana & Luisa Lampignano & Roberta Zupo & Ilaria Bortone & Vito Guerra & Chiara Griseta & Davide Seripa & Vincenzo Solfrizzi & Gianluigi Giannelli & Nicola Quaranta & Giancarlo Logroscino & Antonello Bellomo & Francesco Panza
Received: 1 June 2020 / Accepted: 15 October 2020 # American Aging Association 2020
Abstract The association between late-life depression (LLD) and age-related hearing loss (ARHL) was suggested by preliminary studies, but reliance on LLD subtypes may introduce significant bias. We examined the association between ARHL and LLD according to the age of onset (early-onset depression (EOD) and lateonset depression (LOD)). We investigated the associaM. Lozupone : I. Bortone : V. Guerra : G. Logroscino Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy M. Lozupone (*) : R. Sardone : R. Donghia : F. Castellana : L. Lampignano : R. Zupo : C. Griseta : G. Giannelli : F. Panza (*) Population Health Unit - “Salus In Apulia Study”, National Institute of Gastroenterology “Saverio de Bellis,” Research Hospital, Castellana Grotte, Bari, Italy e-mail: [email protected] e-mail: [email protected] e-mail: [email protected] F. D’Urso : C. Piccininni : I. Di Gioia : A. Bellomo Psychiatric Unit, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy P. Battista Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy E. Resta Department of Cardiac, Thoracic, and Vascular Science, Institute of Respiratory Disease, University of Bari Aldo Moro, Bari, Italy
tion between ARHL and LLD diagnosed according to the Semi-structured Clinical Diagnostic Interview for DSM-IV-TR in 1749 Italian community-dwelling older subjects from the population-based GreatAGE Study, Southern Italy. Peripheral ARHL was assessed as a pure tone average (PTA) threshold > 40 dB hearing level in the better ear- and age-related CAPD as a score of
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