Maternal Fetal Transmission of Human Viruses and their Influence on Tumorigenesis
The human foetus is separated from the maternal blood by the syncytiotrophoblast induced by endogeneous human retrovirus-encoded proteins. This barrier is a highly developed one, which suppors apical-basolateral transport of maternal idiotype and anti-idi
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Gyo¨rgy Berencsi III Editor
Maternal Fetal Transmission of Human Viruses and their Influence on Tumorigenesis
Editor Gyo¨rgy Berencsi III Division of Virology National Center for Epidemiology Gya´li Street 2-6, Bldg C Budapest, Hungary
ISBN 978-94-007-4215-4 ISBN 978-94-007-4216-1 (eBook) DOI 10.1007/978-94-007-4216-1 Springer Dordrecht Heidelberg New York London Library of Congress Control Number: 2012936074 # Springer Science+Business Media B.V. 2012
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Preface
“Maternal fetal transmission of human viruses and their influence on tumorigenesis” is a volume based on several decades of experiences collected in connection with clinical diagnostics and research experience of virologists, pathologists, oncologists and obstetricians. The work of series of PhD students is appreciated first. Achilles’ heels are present on every barriers of the human body including the maternal-fetal barriere. Bidirectional transcytosis were shown to transfer stem cells between the fetus and the mother, but premalignant or malignant cells might be present among them. Latent viruses might be carried by maternalfetal microchimerism into the fetal organs. These viruses might modulate the fetal immune system and the TREG cells can probably i
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