Measuring Oxidants and Oxidative Stress in Biological Systems
This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are des
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Lawrence J. Berliner Narasimham L. Parinandi Editors
Measuring Oxidants and Oxidative Stress in Biological Systems
Biological Magnetic Resonance Volume 34
More information about this series at http://www.springer.com/series/5693
Lawrence J. Berliner • Narasimham L. Parinandi Editors
Measuring Oxidants and Oxidative Stress in Biological Systems
Editors Lawrence J. Berliner Department of Chemistry and Biochemistry University of Denver Centennial, CO, USA
Narasimham L. Parinandi Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine Ohio State University College of Medicine, Dorothy M. Davis Heart and Lung Research Institute
Columbus, OH, USA
ISSN 0192-6020 ISSN 2512-2215 (electronic) Biological Magnetic Resonance ISBN 978-3-030-47317-4 ISBN 978-3-030-47318-1 (eBook) https://doi.org/10.1007/978-3-030-47318-1 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
This volume is dedicated to the editors’ precious grandchildren: Brendan Makoto Berliner Verity Beatrice Lester Evangeline Grace Lester Grier Kiran Parinandi Graley Karthik Parinandi
Preface
It is without question that oxidants (reactive oxygen species [ROS] and reactive nitrogen species [RNS]) mediate oxidative stress and are at the epicenter of biological functions and pathophysiological events. Thus, ROS, RNS, oxygen levels, and the redox state of the biological system (e.g., cells, tissues, the whole organism) should be measured precisely by analytical methods that offer greater sensitivities and suitability for each and every reactive species, including ROS, RNS, oxygen, and redox molecules. In addition, the determination or assessment of b
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